Clinical analysis of thyroid-assocaited ophthalmopathy with optic neuropathy
- VernacularTitle:甲状腺相关眼病性视神经病变的临床分析
- Author:
Zhongyao WU
;
Jianfeng HE
;
Huasheng YANG
- Publication Type:Journal Article
- Keywords:
Graves′ disease;
Optic nerve diseases;
Orbit/physiopathology
- From:
Chinese Journal of Ocular Fundus Diseases
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical manifestations and the effect factors of thyroid-associated ophthalmopath (TAO) with optic neuropathy. Methods The clinical data of 62 cases (120 eyes) of TAO with optic neuropathy diagnosed in 1994-2001 were retrospectively analyzed. Results The incidence of TAO with optic neuropathy was 18.3% in all the simultaneous TAO inpatients, and was more frequently found in the male than in the female ones. The incidence of TAO with optic neuropathy was correlated with orbitono-increase, ocular myopathy, hypertension, hyperlipemia, diabetes, and cardiopathy (P0.05). In 62 patients with the methylprednisolone pulse therapy, the visual acuity improved in 33 (29 0%), improved while the treatment but decreased after stop treating in 29 (24.2%), and no changes in 58 (46.8%). In 63 eyes undergone orbital decompression with methylprednisolone pulse therapy, 59 (93.7%) had better visual acuity. Conclusion The incidence of TAO with optic neuropathy was correlated with orbitono-increase, ocular myopathy, hypertension, hyperlipemia, diabetes, and cardiopathy. Methylprednisolone pulse therapy and orbital decompression are the effective measures for TAO with optic neuropathy.
