Relationship between the type of histopathology and prognosis of contained mucous adenocarcinoma of stomach
- VernacularTitle:含黏液腺癌的胃癌组织病理学的分型与预后的关系
- Author:
Yangkun WANG
;
Fengbo CAI
;
Hui YAN
;
Huaxin LI
;
Xiuli WANG
;
Han YU
;
Songtao CHEN
;
Shunfei LI
- Publication Type:Journal Article
- Keywords:
STOMACH NEOPLASMS/pathol;
ADENOCARCINOMA/pathol;
PROGNOSIS
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the type of histopathology and prognosis of contained mucous adenocarcinoma(CMAC) of stomach and its clinical significance. Methods Eighty-seven cases of CMAC of stomach were observed by means of pathomorphology, histochemistry, immunohistochemistry and follow up etc. Results The malignant behavior of the cancer was significant difference according to the nature and quantity of the CAMC and the primary pathological type of the cancer.The clinical type in simple mucous carcinoma was mainly Borrmann type I;in tubular papilla mucous adenocarcinoma was mainly Borrmman type II; in signet-ring cell mucous carcinoma was mainly Borrmman type IV,and in mixed cell mucous carcinoma was mainly Borrmman type III. There was significant difference in the lymphatic metastasis and survival rate between the 4 groups. Conclusions Correct differentiation of the pathological type of contained mucous adenocarcinoma of stomach is important for guading the treatment and predicting the prognosis.Cathepsin D expression can help for understanding the biological behavior of CMAC of the stomach.