The dose-response relationship of remifentanil and propofol given by TCI for induction of anesthesia
- VernacularTitle:瑞芬太尼复合异丙酚靶控输注诱导时的量效关系
- Author:
Zhiyu CENG
;
Xing XU
;
Xinmin WU
- Publication Type:Journal Article
- Keywords:
Propofol;
Piperidines;
Drug delivery systems;
Dose-response relationship, drug
- From:
Chinese Journal of Anesthesiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of target-controlled infusion (TCI) of remifentanil (R) in various doses in combination of TCI propofol (P) on hemodynamic response to tracheal intubation. Methods Fifty ASA Ⅰ - Ⅱ patients (18 male, 32 female) aged 100 bpm) . The TCI system comprised Graseby 3500 infusion pump controlled by computer program Rugloop which included Marsh and Minto pharmacokinetic parameters. Results Induction time (from start of TCI R + P to LOC) was significantly longer in group RO and R2 than that in group R4, R6 and R8 ( P
