Effects of human urotension Ⅱ on in vivo mesenteric microcirculation in rats
- VernacularTitle:尾加压素Ⅱ对大鼠肠系膜微循环的影响
- Author:
Xiuhua LIU
;
Lirong CAI
;
Fengying LIU
;
Sheng SUN
;
Yue HAN
;
Niu TIAN
;
Chaoshu TANG
- Publication Type:Journal Article
- Keywords:
Urotensins;
Peptides;
Microcirculation;
Intestine, small;
Rtas
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effects of human urotensin Ⅱ (hUII) on in vivo mesenteric microcirculation in rats. METHODS: For recording of microcirculation images in the mesentery, the intestinal loop was mounted on the stage of an intravital microscope equipped with a TV camera. Video images of microcirculation were stored by a video cassette recorder. Temporal changes in internal diameter and microcirculatory velocity of microvesseles were measured by computer using the ImagePro software. The blood flow in intestinal wall was measured with PIMII laser Doppler perfusion Imager (Lisca Sweden). RESULTS: The internal diameters of arterioles and venules in control group were (21.4?2.3) ?m and (38.1?3.6) ?m,respectively. In UII group, the arterioles and venules contracted immediately after treated with UII and up to the peak at 1 min [(14.1?1.4) ?m and (22.2?5.2) ?m vs control,P0.05). The blood flow in intestinal wall increased 1 min after treated with UII and up to high peak at 5 min(6.4?1.1 perfusion unit vs control 4.2?0.9,P
