Clinical Analysis of Angioimmunoblastic T-cell Lymphoma in Children
- VernacularTitle:儿童血管免疫母细胞性T细胞淋巴瘤临床分析
- Author:
Zunke QIN
;
Minghua YANG
;
Huanxiu WANG
- Publication Type:Journal Article
- Keywords:
Angioimmunoblast;
Lymphoma;
Infant
- From:
Journal of Chinese Physician
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the diagnosis and therapy of children angioimmunoblatic T-cell lymphoma (AITL) by analyzing the clinical parameters of AITL. Methods The clinical data of 6 patients with AITL in the recent 10 years were retrospectively analyzed. Results The main symptoms of AITL had fever,skin rash,general lymphadenopathy, hepatosplenomegaly, anemia and polyclonal hypergammaglobulinemia. The pahologic morphology of AITL was what was known as "Triad", the immunophenotype of both the T-cell and B-cell was positive, and B-cell's one was main. Conclusion AITL is high malignant, and only lymphaden biopsy could confirm the diagnosis of AITL. Its prognosis is variable in different patients. The discrepancy of prognosis between children and adults is worthy of study, and individualized therapy of AITL must be adopted.
