The correlation between expression of gastrin, somatostatin and cell apoptosis, p53 gene in colonic carcinoma
- VernacularTitle:大肠癌组织生长抑素、胃泌素表达与细胞凋亡及p53基因的相关性研究
- Author:
Jiading MAO
;
Pei WU
;
Xianghou XIA
;
Jiqun HU
;
Wenbin HUANG
;
Guoqiang XU
- Publication Type:Journal Article
- Keywords:
Colonic neoplasms;
Somatostatin;
Gastrin;
Gene,p53;
Apoptosis index
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between the expression of somatostatin (SS), gastrin (GAS), apoptosis index (AI),and p53 gene in colonic carcinoma. Methods The expression of GAS, SS, p53 and apoptosis cell were detected by immunohistochemistry (streptavidin-biotin-pero xidase complex, SABC) and in situ apoptosis detecting technic (TUNEL) . Results AI is higher in SS high and middle expression cases than in low expression cases(q=5.06,q=3.95,P