An experimental study on the prevention of spinal ischemia caused by cross-clamp of thoracoabdominal aorta
- VernacularTitle:预防胸腹主动脉阻断后脊髓缺血性损伤的实验研究
- Author:
Fuxian ZHANG
;
Changming ZHANG
;
Lu HU
- Publication Type:Journal Article
- Keywords:
Injury, spinal;
Ischemia;
Hypothermia;
Prostaglandins E
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prevent and manage spinal ischemia caused by cross-clamping the thoracoabdominal aorta often undertaken in clinical surgical practice. Methods Forty-five rabbits were divided for 3 experiments. A variety of vasoactive agents were used to manage spinal ischemia; The effect of cerebrospinal fluid drainage was evaluated; Hypothermia was used to alleviate the spinal ischemia injury. Results Among the above three experiments neuron degeneration was the mildest in hypothermia group though prostaglandin and cerebrospinal fluid drainage do have some positive effects. Conclusion It was suggested that administration of hypothermia and prostaglandin are the most effective for the prevention of spinal ischemic injury during major thoracoabdominal aorta surgery.
