Effect of hemofiltration on imbalance of pro- and anti-inflammatory cytokines in severe acute pancreatitis patients
- VernacularTitle:血液滤过治疗对重症急性胰腺炎患者血浆炎性细胞因子水平的影响
- Author:
Jing TAO
;
Chunyou WANG
;
Zhiyong YANG
;
Libo CHEN
;
Jianxiong YU
;
Jiongxin XIONG
;
Feng ZHOU
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Tumor necrosis factor;
Interleukins
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of single short (SS) veno-venous hemofiltration and intermittent short (IS) veno-venous hemofiltration on imbalance of pro- and anti-inflammatory cytokines in severe acute pancreatitis (SAP) patients. Methods There were 17 and 21 SAP patients indicated for hemofiltration respectively enrolled for (SS) veno-venous hemofiltration (SS group) and IS veno-venous hemofiltration (IS group).Twenty SAP patients admitted and indicated for hemofiltration but not receiving the management during the same period served as control. Plasma levels of TNF-?,IL-6,IL-8,and IL-10 were measured. APACHE Ⅱ scores and fluid balance were used to evaluate patients′ condition. Results APACHE Ⅱ scores in both SS and IS groups declined significantly at day one after admission(P
