Study on the Bacterial Endotoxin Test for Compound Diclofenas Sodium and Lidocaine Hydrochloride In-jection
- VernacularTitle:双氯芬酸钠盐酸利多卡因注射液细菌内毒素检查法的研究
- Author:
Qizhi WEI
- Publication Type:Journal Article
- Keywords:
compound diclofenac sodium and lidocaine hydrochloride injection;
bacterial endotoxin test;
interference test
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a bacterial endotoxin test for compound diclofenac sodium and lidocaine hydrochlo?ride injection(CDL).METHODS:The limitation of endotoxin in CDL was determined and a interference test was performed to determine the maximum non-interference concentration.RESULTS:CDL could interfere the detection of bacterial endotoxin,which could be overcome through300-fold dilution of the preparation.CONCLUSION:The bacterial endotixin test can be used to replace the detection of pyrogen in CDL.
