Infection occurred with in short-term after orthotopic liver transplantation
- VernacularTitle:原位肝移植术后近期感染分析
- Author:
Ke CHENG
;
Zufa HUANG
;
Shaihong ZHU
;
Maozu ZHANG
;
Qifa YE
;
Yujun ZHAO
- Publication Type:Journal Article
- Keywords:
LIVER TRANSPLANTATION;
POSTOPERATIVE COMPLICATOAS;
BACTERIAL INFECTIONS
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the diagnosis and prophylaxis of postoperative infections within 1 month after orthotopic liver transplantation(OLT). Methods Clinical date of 38 consecutive patients who underwent OLT at our institution from 2001 to 2003 were retrospectively reviewed. Result Eighteen patients( 47.4% ) developed twenty-nine times infection after operation .Respiratory tract and peritoneum were the common infectious sites(37.9% and 24.1%). Enterobacter cloacae(8 of 29, 27.6%) , Escherichia coli(7 of 29, 24.1%),staphylococcus aureus(6 of 29, 20.7%) were the commonest bacterial.The mortality of infection was 38.9%(7/18). Identified risk factors for infection including: previous transplantation ; duration of operation; transfusion requirements during surgery; type of biliary anastomosis; delayed restoration of gastrointestinal function and persistent postoperative hyperglucocemia . Perioperative decontamination of the digestive tract had a protective effect. Conclusions Infections are a major cause of death among liver transplant recipients. Reducing risk factors of infection and perioperative decontamination of the digestive tract may decrease the occurrence of postoperative infection.