Effects of monocyte-endothelium interaction on the expression of CD36 in monocytes
- VernacularTitle:单核细胞与内皮细胞的相互作用对单核细胞CD36表达的影响
- Author:
Rui LIU
;
Aiqun MA
;
Chunyuan HAO
;
Jinjun LIU
;
Guangdao GAO
- Publication Type:Journal Article
- Keywords:
Arteriosclerosis;
Monocytes;
Endothelial cells;
Macrophage colony-stimulating factor;
Antigens;
CD36
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To examine the effects of monocyte-endothelium interaction on the expression of CD36 in monocytes and observe the functions of cytokines in this process. METHODS: The monocytes and endothelial cells were cultured alone or cocultured together to form different cell culture conditions. The level of M-CSF in culture medium was determined by enzyme linked immune sandwich assay(ELISA) technique, and the expression of CD36 in monocytes was determined by flow cytometry. RESULTS: The expression of CD36 in monocytes was low in monocytes cultured alone but increased significantly when monocytes and endothelial cells were cocultured(P