Serum sCD44s and sCD44v6 levels in breast cancer patients
- VernacularTitle:血清sCD44s及sCD44v6变化与乳腺癌的初步研究
- Author:
Zhenlin YANG
;
Shusen ZHENG
;
Ronghua WANG
;
Qiangpu CHEN
- Publication Type:Journal Article
- Keywords:
Cell adhesion molecules;
Anfigene;
CD44;
Breast neoplasms
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the clinical significance of detecting sCD44s and sCD44v6 in breast carcinoma.METHODS: Levels of serum soluble CD44 standard (sCD44s) and CD44 variant 6(sCD44v6) were detected by ELISA in 38 cases of breast cancer, 15 cases of benign breast diseases and 40 normal controls. RESULTS:The serum levels of sCD44s and sCD44v6 were significantly higher in patients with breast cancer than those with benign disease or normal controls. The serum concentrations of sCD44s and sCD44v6 in patients with stage Ⅲ, Ⅳ were significantly higher than those in patients with stage Ⅰ, Ⅱ(P
