Clinical Application of ~(99m) Tc-HL91 Hypoxia Imaging in Lung Cancer
- VernacularTitle:~(99m)Tc-HL91肺癌乏氧显像的临床应用
- Author:
Bo DENG
;
Huan XIAO
;
Xiaofeng CHEN
- Publication Type:Journal Article
- Keywords:
Lung cancer;
99m Tc-HL91;
Hypoxia;
Nuclein scintigraphy
- From:
Journal of Chinese Physician
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of 99m Tc-HL91 hypoxia imaging in the diagnosis and treatment of lung cancer. Methods 99m Tc-HL91 hypoxia imaging was performed in 72 patients with primary lung cancer. The qualitative analysis and semi-quantitative analysis of the early and delayed images were also performed. 65 patients underwent chemotherapy were divided into 2 groups by the T/N value of delayed images, and the curative efficacy in both the two groups was compared. Results The sensitivity of 99m Tc-HL91 hypoxia imaging for diagnosing lung cancer was 86 1% in early imaging and 98 6% in delayed imaging. The results of semi-quantitative analysis in different pathological types of lung cancer hadn’t obvious difference. The curative efficacy of the patients with low uptake was better than that of the patients with high uptake in 65 patients underwent chemotherapy, difference of which had significant(P
