The Relationship Between the Serum Level of Neuron-specific Enolase and the Severity and Prognosis of Head Injuried Patients
- VernacularTitle:神经元特异性烯醇化酶在颅脑损伤中的意义
- Author:
Zhifei WANG
;
Daguang LIAO
;
Shanchu YI
- Publication Type:Journal Article
- Keywords:
Head injury;
Neuron-specific enolase;
Prognosis;
Radioimmunoassay
- From:
Journal of Chinese Physician
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the serum concentration of neuron-specific enolase (NSE) and the brain damage severity and the prognosis of acute head injuried patients. Methods Early serum levels of NSE were measured in 70 patients with acute head injury by radioimmunoassay. The concentration of NSE was analysed by combining with GCS and GOS systems. Results NSE levels in serum of patients with major(a), minor(b) head injuries and control individuals(c) were (25 78 ? 10 80)ng/ml, (19 58 ? 8 91)ng/ml and (9 51 ? 2 79)ng/ml respectively, differences of which were significant (P a-b
