The Correlation Between Mood Disorders and Nerve Growth Factor Receptor Expression in Lesions of Psoriasis
- VernacularTitle:银屑病患者负性情绪与神经生长因子受体表达的相关性研究
- Author:
Xibao ZHANG
;
Rongguo HE
;
Zhihua WU
- Publication Type:Journal Article
- Keywords:
Psoriasis;
Receptor,nerve growth factor;
Mood disorders
- From:
Chinese Journal of Dermatology
1995;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the molecular mechanism of mood disorders in psoriatic patients.Methods The expression of nerve growth factor receptor p75(NGFR p75)and p140trkA were detected by immunohistochemical technique.The patients' mood was measured with self-rating anxiety scale(SAS)and self-rating depression scale(SDS).Results There is a positive correlation of the expressions of NGFR p75and p140trkA with the patients' mood disorders in psoriatic patients.Conclusion NGF and its receptors are the important substance served as a mediator of the mood disorders affecting psoriatic patients' condition.
