Changes of vascular endothelial growth factor in gastric mucosa in portal hypertensive gastropathy
- VernacularTitle:门静脉高压症胃黏膜血管内皮生长因子变化的研究
- Author:
Zhonghua SHANG
;
Xunyang LIU
;
Feizhou HUANG
;
Wanpin NIE
;
Shaihong ZHU
;
Shuping REN
- Publication Type:Journal Article
- Keywords:
Hypertension,portal;
Endothelial growth factors;
Reverse transcriptase polymerase chain reaction
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of VEGF in the development of portal hypertensive gastropathy(PHG). Methods Forty-four portal hepertensive patients were investigated according to with or without PHG. The degree and the location of PHG were recorded. The specimens were obtained to perform RT-PCR to measure VEGF mRNA. Results VEGF mRNA in severe (3.48?1.02) or moderate PHG (2.28?0.33) with portal hypertension was higher than that in control (1.40?0.23) and those (1.51?0.32) with portal hypertension without PHG( P