The expression of rdxA gene in Helicobacter pylori isolates with metronidazole resistance
- VernacularTitle:对甲硝唑耐药幽门螺杆菌中rdxA基因的表达
- Author:
Hui LIN
;
Xiaowei PENG
;
Liping HE
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Metronidazole;
Drug resistance;
RdxA gene
- From:
Chinese Journal of Digestive Endoscopy
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
256 mg/L) are resistant to metronidazole by two tests. The level of transcripts of rdxA genes significantly reduced the total RNA in Helicobacter pylori grown with metronidazole compared to that without metronidazole. And the expression of the galE gene used as the control was unchanged. Conclusion The low expression of the rdxA gene may play a role in the development of metronidazole high resistant Helicobacter pylori isolates.
