Microvessel Density and CD44v6 Expression in Uterine Cervical Squamous Carcinoma and Their Clinical Significance
- VernacularTitle:子宫颈鳞癌中微血管密度与CD44v6表达及其临床意义
- Author:
Zhengwen XIONG
;
Hong SU
;
Yong HUANG
- Publication Type:Journal Article
- Keywords:
Uterine cervical squamous carcinoma;
Microvessel density;
CD44v6;
Lymph node metastasis
- From:
Journal of Chinese Physician
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the microvascular density(MVD) and CD44v6 expression in uterine cervical squamous carcinoma to evaluate their clinical significance. Methods Immunohistochemical staining (LSAB method) by using antibodies against CD 34 and CD44v6 was performed on archival specimens of 50 cases of human uterine cervical squamous carcinoma and 10 cases of normal cervical tissue. Results MVD was greater in metastatic tumors than that in nonmetastatic tumors and normal control. The expression of CD44v6 was higher in metastatic tumors than that in nonmetastatic tumors and normal control. MVD and CD44v6 expressions were significantly related to lymph node metastasis(P
