Expression of PCNA and Ki-67 in Thyroid Neoplasms and Their Correlation
- VernacularTitle:甲状腺肿瘤细胞PCNA和Ki-67抗原表达及其相关性研究
- Author:
Kelun CHENG
;
Potao LUO
;
Yuming YANG
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasm;
PCNA;
Ki-67
- From:
Journal of Chinese Physician
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the expression of PCNA and Ki-67 proliferation antigens in thyroid neoplasms and to study diagnostic value of expression of PCNA and Ki-67 in benign and malignant neoplasms of thyroid. Methods The expression of PCNA and Ki-67 in 76 thyroid neoplasms was examined by immunohistochemical method(EnVision MT ). Results Among the 39 thyroid adenomas(TA), the indices of PCNA and Ki-67 were 0 16?0 09(39/39) and 1 49?1 15(39/39) respectively; Among the 37 thyroid carcinomas(TC), the indices of PCNA and Ki-67 were 0 43?0 31(37/37) and 2 13?1 52(37/37) respectively. The differences of both the PCNA and Ki-67 indices between TA and TC were significant(P
