Experiment Research of Alteration of Blood Lipids,Glucose and Blood Goagulation Factors in Hyperlipoidemia
- VernacularTitle:高脂血症血脂和血糖及凝血因子变化的实验研究
- Author:
Rongde TANG
;
Zhihua LUO
;
Sanyuan JIANG
- Publication Type:Journal Article
- Keywords:
Hyperlipoidemia;
Animal model;
Clinical case;
Blood glucose;
Blood coagulation factor
- From:
Journal of Chinese Physician
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes and correlations of the blood lipids, glucose and blood coagulation factors in the animal models and patients with lipodystrophia. Methods The models of hyperlipoidemia were set up in 30 rabbits, and 40 cases of the hyperlipoidemia and 40 cases of the healthy subjects randomly were enrolled in this study. Their blood lipids, glucose and coagulation factors were detected. Results The serum levels of TC,TG,LDL-C and Glu in the rabbit models and patients with hyperlipoidemia notably increased compared with controls(P0 05). HDL-C level increased in the rabbit models(P0 05). Conclusions The change of the blood lipids level in the rabbit models was different from that of the patients with hyperlipoidemia. But both may company the abnormality of carbohydrate metabolism, and hyperlipoidemia may affect the endogenous blood coagulation system to cause the blood to present the high coagulation.
