Levels of Endothelin and ?-Human Chorionic Gonadotropin in Patients with Severe Pregnancy Induced Hypertention
- VernacularTitle:妊高征患者血中ET和?-hCG关系初探
- Author:
Jie ZHANG
;
Yinyan SHE
- Publication Type:Journal Article
- Keywords:
Pregnancy induced hypertension;
Endothelin;
?-human chorionic gonadotropin
- From:
Journal of Chinese Physician
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate levels of endothelin (ET) and ?-human chorionic gonadotropin (?-hCG) and the relationship between them in patients with pregnancy induced hypertension(PIH), and to investigate the role of ET and ?-hCG in the pathogenesis of PIH. Methods ET and ?-hCG serum levels of 30 patients with severe PIH, 20 normal term pregnant women and 20 nonpregnant health reproductive age women were determined by radioimmunoassay. Results ET and ?-hCG levels were significantly higher in patients with severe PIH than those in two control groups(P0 05). Conclusions The increased levels of ET and ?-hCG as well as their positive correlation suggested that the dysfunction of the placental cells may be associated with the endothelial cell damage in severe PIH patients.
