Serum Levels of Matrix Metalloproteinases-9 in Patients with Systemic Lupus Erythematosus
- VernacularTitle:系统性红斑狼疮患者血清基质金属蛋白酶-9的检测
- Author:
Wenhao YIN
;
Zhang BAO
;
Min ZHENG
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus, systemic;
Gelatinase B;
Tissue inhibitor of metalloproteinase-1
- From:
Chinese Journal of Dermatology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the serum levels of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in patients with systemic lupus erythematosus (SLE) and their clinical significances. Methods The serum concentrations of MMP-9 and TIMP-1 were measured by ELISA in 46 patients with SLE and age- and sex-matched normal controls. Results ①Serum levels of MMP-9 was significantly decreased in patients with SLE compared with those in normal controls (P
