The effects of enteral feeding and parenteral nutrition on the 19S regulator in skeletal muscle of the scald rats
- VernacularTitle:肠道喂养和肠外营养对烫伤大鼠骨骼肌19S调节复合体作用的影响
- Author:
Yinling TAN
;
Shiliang WANG
;
Yanling DONG
- Publication Type:Journal Article
- Keywords:
ENTERAL NUTRITION;
PARENTERAL NUTRITION;
BURNS/ther;
SKELETAL MUSSLE;
REGULATOR
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effectrve approach of the nutrition support in burn patients. Methods The means of immuno-precipitation-deduction,ELISA and fluore-photometion were used to test the change of activities,protein expression of the 19S regulator and the rate of protein degradation in skeletal muscle in scard rats with enteral feeding or parenteral nutrition. Results Compared with parenteral nutrition , enteral feeding could markedly reduce the activity and protein expression of the 19S regulator ,and the digeneration of skeletal muscle was also lower. Conclusions The early enteral feeding can distinctly inhibit the system of 26S proteasome , thereby reduce the protein degradation of skeletal muscle in scald rats,which may be benefical to the metabolic modulation of the burned patients.