Expression of TGF-?_1 and CDK4 in Normal Esophageal Mucosa and Esophageal Squamous Cell Carcinoma
- VernacularTitle:食管正常黏膜及鳞癌中TGF-?1、CDK4蛋白水平的研究
- Author:
Junhua LIU
;
Gongsheng SHI
;
Jiahai SHI
- Publication Type:Journal Article
- Keywords:
Esophageal SCC;
TGF-? 1;
CDK4;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the roles of TGF-? 1 and CDK4 in esophageal squamous cell carcinoma (SCC).Methods The expression of TGF-? 1 and CDK4 was examined in 50 cases of esophageal squamous cell carcinoma and 10 cases of normal esophageal mucosa with SABC immunohistochemical technique. All the samples were stained by HE to confirm their pathologic characters. The number of positive cells was counted under microscope. The data were analyzed with x 2 tests and t test.Results TGF-? 1 and CDK4 positive cells were significantly higher in esophageal SCC than those in the normal esophageal mucosa (P
