Effects of HIF-2? and VEGF on Angiogenesis and Metastasis of Renal Cell Carcinoma
- VernacularTitle:HIF-2?、VEGF与肾细胞癌血管生成、癌转移的关系
- Author:
Peng KONG
;
Wenli HUANG
;
Yinfeng LIU
- Publication Type:Journal Article
- Keywords:
Renal cell cancer;
HIF-2?;
VEGF
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expression of HIF-2? and VEGF in renal cell carcinoma (RCC) and their correlation with angiogenesis and metastasis of renal cell carcinoma. Methods Expression of HIF-2? and VEGF were assessed by immunohistochemical straining in 48 cases of renal cell carcinomas. Results In 48 cases of renal cell carcinomas, positive rate of HIF-2? was 70.8%. Strong expression of HIF-2? was observed in 12 cases, moderate in 10 cases, weak in 12 cases and no expression in 14cases.There was a significant difference in HIF-2? expression between carcinoma tissues and control tissues (P
