The Effects of Short-term Intensive Insulin Treatment on Pancretic ? Cell Function in Newly Diagnosed Type 2 Diabetic Patients
- VernacularTitle:短期胰岛素强化治疗初诊2型糖尿病对胰岛?细胞功能影响的观察
- Author:
Huazhu LI
;
Ming WANG
;
Xianghua LIU
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Insulin;
Therapeautics;
Pancreatic beta cells
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
13.1mmol/L were treated by 2 weeks short-term intensive insulin treatment. FBS, Fasting blood insulin(FINS), glycosylated hemoglobin A1c (HbA1c), 2 hours postprandial blood sugar(PBS 2), Homa ? and Homa IR were measured and compared between pre-treatment and post-treatment. Results After 2 weeks short-term intensive insulin treatment, the excellent control of FBS, PBS 2 in 23 out of 27 patients were achieved respectively in (5.6?2.3)days and (8.5?3.5)days. Homa ? significantly increased, and HbA1c and Homa IR decreased comared with pre-treatment. Conclusions The excellent glycemia control and improvement of ?-cell function can be induced by short-term intensive insulin treatment in newly diagnosed type 2 diabetic patients with severe hyperglycemia.
