An experimental study of bone marrow seeded vascular graft in venous system
- VernacularTitle:骨髓种植人工血管在静脉系统的实验研究
- Author:
Xiaoming ZHANG
;
Wei LI
;
Qingle LI
;
Zhonggao WANG
- Publication Type:Journal Article
- Keywords:
Blood vessel prosthesis;
Veins;
Bone marrow seeding
- From:
Chinese Journal of General Surgery
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate venous substitutes and investigate the effect of bone marrow seeded vascular graft in venous system. Method Knitted double velour Dacron grafts were implanted in the infrarenal vena cava in 8 mongrel dogs. Four grafts were seeded by autogenous bone marrow, and four were treated by autogenous plasma. The grafts were harvested at postop day 10.Light and electron microscopy were used to measure the thickness and endothelialization of neointima. The level of 6-keto-PGF1-alpha and TXB2 were also measured. Results All bone marrow seeded grafts and 2 of 4 controls were patent. The thickness of neointima in the seeded grafts was significantly thinner than that in the control(P
