Study of the Efficacy of Losartan on Unstable Angina
- VernacularTitle:洛沙坦治疗不稳定心绞痛的临床观察
- Author:
Baolai YI
;
Xueyu YU
;
Zhaoxin QIAN
- Publication Type:Journal Article
- Keywords:
Unstable angina;
Losartan;
Angiotensin Ⅱ receptor antagonist
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of losartan on unstable angina (UA).Methods In a period of 14 days, 83 subjects with UA were randomly divided into 2 groups (group T and C). In group C, nitroglycerin 10-20mg plus 5%glucose 250ml was given by vein drips twice daily. Aspirin 150mg/day and metoprolol 12.5～25mg twice daily were given too. In group T, losartan, in a single dose of 50mg/day was given in addition to treatments of group A. Frequency of angina pectoris, rate pressure product, ST segments changes in 12 lead ECG and several heart function indexes in echocardiography were investigated at the beginning and the end of the study.Results The differences of efficacy between the two groups were significant ( P
