Study on the Stability of Amoxicillin Sodium and Clavulanate Potassium for Injection in Sodium Chloride Injection Solution
- VernacularTitle:注射用阿莫西林钠克拉维酸钾与氯化钠注射液配伍稳定性考察
- Author:
Jingxian ZHANG
;
Zizhong LIN
;
Xianjiao HUANG
- Publication Type:Journal Article
- Keywords:
Amoxicillin sodium and Clavulanate potassium for injection;
sodium chloride injection;
compatibility;
stability
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the stability of amoxicillin sodium and clavulanate potassium for injection in sodium chloride injection solution so as to offer a scientific basis for rational use of drug in clinical practice.METHODS:The external appearance and pH values of the mixed solution were observed,and the contents of Amoxicillin sodium and Clavulanate potas?sium were determined by HPLC method at5℃,25℃and37℃within3hours.RESULTS:The stability was related to the temperature and sunlight.CONCLUSION:The mixed solution is instable and should not be put in storage for long time.
