The relation of change of intestinal permeability with early operation in acute pancreatitis
- VernacularTitle:肠道通透性改变与急性胰腺炎早期手术探查
- Author:
Yi TAI
;
Haiping MENG
;
Li WANG
- Publication Type:Journal Article
- Keywords:
PANCREATITIS/physiopathol;
INTESTINAL MUCOSA/physiopathol
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the change of intestinal permeability in patients with acute pancreatitis (AP) to investigate the indication of early operation in AP patients. Methods Serum concentrations of glutamine, endotoxin and urine lactulose/mannito (L/M) ratio were measured and compared at different time in 18 AP patients received non-operative treatment and 7 underwent operation . Results Serum concentrations of glutamine, endotoxin and urine lactulose mannito (L/M) ratio were significantly higher in operation treatment AP patients than those in non-operation treatment AP patients. Conclusion In the early course of AP, continued increased intestinal permeability and serum concentration of endotoxin is the indications of operation.
