Progress in mitochondrial nitric oxide synthase
- VernacularTitle:线粒体一氧化氮合酶的研究进展
- Author:
Xiaosi SUN
;
Dunyong TAN
;
Huadong WANG
;
Liang YAN
- Publication Type:Journal Article
- Keywords:
Nitric-oxide synthase;
Mitochondria
- From:
Chinese Journal of Pathophysiology
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Nitric oxide (NO) is an intra- and intercellular messenger with a broad spectrum of activities in the central nervous system, cardiovascular and immune systems. Mitochondrial nitric oxide synthase(mtNOS), which might be a new form of NOS in mitochondria, has been discovered to be active in the regulation of mitochondrial respiration, energy metabolism and many pathophysiological processes. In this review, the location, properties, physiological and pathophysiological significance of mtNOS were summarized.