Relationship Between the Expression of PDGF and PDGFR and MVC in the Gastric Carcinoma
- VernacularTitle:PDGF,PDGFR在胃癌组织中的表达及与微血管计数的关系
- Author:
Dongcai LIU
;
Rongguo LI
;
Jianpin ZHOU
- Publication Type:Journal Article
- Keywords:
Angiogenesis;
Growth factor;
Receptor;
Gastric neoplasma
- From:
Journal of Chinese Physician
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the expression of PDGF and PDGFR and MVC in human gastric carcinoma. Methods The expression of PDGF and PDGFR in 57 cases with gastric carcinoma was detected by immunohistochemical method of avidin-biotin complex in formalin-fixed and routinely paraffin-embedded tissue sections. Results The expression of PDGF and PDGFR was significantly related to the infiltrative depth and regional lymph nodes metastasis of gastric carcinoma. The positive rates of PDGF and PDGFR in the cases with invasive depth over 2/3 muscular layer were 61 8% and 58 8% respectively, which were obviously higher than those(26 1%, 26 1%) in the ones with invasive depth less 2/3 muscular layer(P
