Determination of Content of Ceftizoxime by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定头孢唑肟钠的含量
- Author:
Aichun YI
;
Shunzhi ZHANG
;
Difang CHEN
- Publication Type:Journal Article
- Keywords:
RP-HPLC;
ceftizoxime;
content
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the content of ceftizoxime for injection METHODS:A RP-HPLC method was established,the polarls C18 was used as analysis column The mobile phase consisted of 0 23% sodium hydrogen phosphate and 0 14% trisodium buffer-acetonitrile(85∶15),the flow rate was 1 0ml/min,the detection wavelength was 254nm RESULTS:The linear range of ceftizoxime was 4 1 462～37 3 156?g/ml,r=0 9 999 The relative standard deviation was 0 6% CONCL_USION:The method is rapid,accurate and suitable for determination of content of ceftizoxime for injection
