Clinical Study on Intra-Amiotic Administration of Pulmonary Surfactant for Neonatal Respiratory Distress Syndrome Prophylaxis
- VernacularTitle:羊膜腔内注射肺表面活性物质预防新生儿呼吸窘迫综合征的临床研究
- Author:
Jianping ZHANG
;
Yinglan WANG
;
Yunhui WANG
- Publication Type:Journal Article
- Keywords:
Amnion;
Injections, intralesional;
Pulmonary surf actants;
Respiratory distress syndrome;
Infant, newborn,diseases
- From:
Chinese Journal of Perinatal Medicine
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo discuss the effects and security o f intra-anmiotic administration of pulmonary surfactant for neonatal respiratory distress syndrome prophylaxis.MethodsForty-five cases of pr eterm delivery with immature fetal lungs were divided into two groups. Fifteen w omen of the study group were administered one dose of pulmonary surfactant into the amniotic cavity and delivered in several hours. Nothing was injected into th e amniotic cavity of the 30 women in the control group. The proportion of NRDS, mortality and the time in hospital were analyzed to make clear whether there wer e any differences between the two groups.ResulstsThere was n o difference between the two groups for neonatal Apgar score. Foam test demonstr ated that the proportion of lung maturity of the neonates was:56.3%(9/16)in the study group, 13.3%(4/30)in the control group,(P
