Effect of Extracts of Herba(RPMP) on the Growth and Proliferation of Cultured Melanocytes
- VernacularTitle:单味中药对体外培养的黑素细胞生长及迁移的影响
- Author:
Kuanhou MU
;
Xianqi ZHANG
;
Bing YU
- Publication Type:Journal Article
- Keywords:
Melanocyte;
Herba(Radix polygoni multiflori preparata);
Proliferation;
Migration
- From:
Journal of Chinese Physician
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study of the effect of traditional Chinese medicine(TCM): Herba radix polygoni multiflori preparata (RPMP) on the cultured melanocytes(MC). Methods Extracts of TMC RPMP treated the cultured melanocytes, and tyrosinase activity, melanin level and proliferation of the cells were determined. Meanwhile, method of micropore filter was used to measure the ability of cell migration. Results TCM RPMP markedly promoted the proliferation and migration of MC in a dose-dependent manner at a range of 0～150?g/ml. Conclusions TCM RPMP can promote the proliferation and migration of MC in vitro. And it suggests that this drug could be used to treat vitiligo.
