Effect of Dexamethasone with Subdose Ketamine on Restraining the Pulling-dragging Reflex During Appendectomy
- VernacularTitle:地塞米松复合氯胺酮抑制阑尾牵拉反应的效果观察
- Author:
Shaohua MIAO
;
Hongxia ZHU
- Publication Type:Journal Article
- Keywords:
Dexamethasone;
Ketamine;
Pulling-dragging reflex
- From:
Journal of Chinese Physician
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of dexamethasone with subdose ketamine on restraining the pulling-dragging reflex during appendectomy. Methods 114 ASA grade Ⅰ～Ⅱpatients of appendectomy undergoing T 11 ～L 1 epidural anesthesia were randomly divided three groups,each group containing 38 cases. Group Ⅰ recieved the dexamethasone 10mg and ketamine 0 5mg/kg by venous injection before opening abdominal cavity, groupⅡ received pethidine 50mg and droperidol 2 5mg before begining operation, and group Ⅲ without any drugs served as control. The pulling-dragging reflex of appendix, the sedative state at pulling-dragging appendix and the change of pulse oxygen saturation (SpO 2) or mean arterial pressure (MAP) were recorded and analyzed. Results The excellent rates of groupsⅠ, Ⅱ and Ⅲ were 100%, 81 58% and 18 42% respectively,and there was significant difference between group I and the other groups (P
