Effects of Early Enteral Feeding on the Preservation of Intestinal Mucosal Barrier in Severely Burned Patients
- VernacularTitle:早期肠道喂养在降低烧伤后肠黏膜通透性中的作用
- Author:
Yizhi PENG
;
Zhiqiang YUAN
;
Guangxia XIAO
- Publication Type:Journal Article
- Keywords:
Early enteral feeding;
Intestinal mucosal barrier;
Burn
- From:
Journal of Chinese Physician
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of early enteral feeding on the preservation of intestinal mucosal barrier in severely burned patients. Methods Twenty-two patients with severe burn were randomly divided into early enteral feeding group (EF) and delayed enteral feeding group (DF). The levels of serum endotoxin and TNF-? were dynamically detected in the patients of both groups, and two unmetabolized sugars (lactose and mannitol) were orally administered in these patients on 1d, 3d and 5d of postburn. The concentrations of lactose and mannitol in urinary and the L/M ratio were observed. Intestinal permeability was assessed by the L/M ratio. Results The levels of serum endotoxin and TNF-? in severely burned patients were significantly higher than in normal (P
