Study on Expression of Fas and Fas Ligand on Peripheral Blood Lymphocyte and Soluble Fas in Pa-tients with Vitiligo
- VernacularTitle:白癜风患者外周血淋巴细胞Fas及Fas配体和可溶性Fas的研究
- Author:
Hongyang LU
;
Bing XU
;
Weimin CAI
;
Beiling WU
;
Liming RUAN
;
Minwei LI
;
Weiwei FAN
;
Yan JIANG
;
Bin SHEN
;
Xiaojing SONG
- Publication Type:Journal Article
- Keywords:
Vitiligo;
Antigens,CD95
- From:
Chinese Journal of Dermatology
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of Fas antigen,Fas ligand(FasL)and soluble Fas(sFas)in the pathogenesis of vitiligo.Methods The expression of Fas and FasL on peripheral blood lym-phocyte(PBLC)was detected by flow cytometry.Serum sFas was quantitated using a dual antibody sandwich enzyme-linked immunosorbant assay(ELISA).Results The expression of Fas and FasL was significantly de-creased in patients with vitiligo vulgaris(43.45%and58.40%)than those in normal controls(58.30%and64.65%)(P
