TGF-?-activated MAPK cascade and its regulation on cells
- VernacularTitle:转化生长因子?的丝裂原激活蛋白激酶通路及其对细胞的调节作用
- Author:
Dongying XUE
;
Jiahe HONG
- Publication Type:Journal Article
- Keywords:
Transforming growth factor beta;
Mitogen-activated protein kinases;
Signal transduction
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Transforming growth factor-?(TGF-?) is a multifunctional growth factor. It plays a very important role in the growth, dif ferentiation, migration, apoptosis of cells and production of extracellular matr ix throughout many signaling pathways. MAPK cascade is one of those signaling pa thways. TGF-? can activate MAPKs and fulfill its multiple regulation on a varie ty of cells.
