Expression and significance of tumor suppressor gene PTEN in colorectal cancer
- VernacularTitle:抑癌基因PTEN在人大肠癌中的表达及其意义
- Author:
Guobao ZHENG
;
Yuanhe WANG
;
Chunfang GAO
;
Hongyang WANG
;
Xingwang WAN
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
KG1Gene expressionHJHK
- From:
Chinese Journal of General Surgery
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of tumor suppressor gene PTEN in colorectal cancer. Methods Using Northern blot,immunohistochemistry, colorectal carcinoma was examined in 47 cases. ResultsKG1 The expression of PTEN mRNA in colorectal cancer was lower than that in paired para-carcinoma tissues( P