Clinical Observation of Carboplatin Combined with Poclitaxel in Treatment of NSCLCⅢb andⅣ
- VernacularTitle:紫杉醇联合卡铂治疗Ⅲb期和Ⅳ期非小细胞肺癌的临床观察
- Author:
Yulong CHENG
;
Yongzhi ZHUANG
- Publication Type:Journal Article
- Keywords:
Paclitaxel;
Carboplatin;
combination;
NSCLC;
observation of therapeutic effect
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the therapeutic effect and adverse reactions of Carboplatin combined with Paclitaxel in treatment of NSCLC.METHODS:37patients with pathologically or cytologically proved NSCLCⅢb orⅣreceived treat?ment.Paclitaxel(150mg/m 2 )in saline iv drip for4-6h and Carboplatin(AUC6)iv drip alteratively administrated for21days.At least2therapeutic courses were carried out.RESULTS:Among37patients,3had complete remission,15partial re?mission13kept stable and6were progressive with a total effective rate of48.6%and one-year survival rate of51.3%.The common adverse reactions were muscular soreness and bone-marrow inhibition,however,most patients could tolerate the side effects.CONCLUSION:The therapeutic effect of Carboplatin and Paclitaxel on advanced NSCLC is reliable and the patients are tolerant of the side effects.
