The effect of FK506 on expression of TNF-? mRNA in isolated liver with reperfusion
- VernacularTitle:FK506对离体肝再灌注后TNF-? mRNA表达的影响
- Author:
Zhiliang SU
;
Haoliang ZHAO
;
Qiguo CHENG
;
Tieyan ZHU
;
Xueliang YANG
;
Huawe GUO
- Publication Type:Journal Article
- Keywords:
LIVER/pathol;
REPERFUSION INJURY;
DISEASE MODELS,ANIMAL;
IN VITRO;
FK506
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of FK506 on the expression of TNF -? mRNA in isolated liver with reperfusion. Methods After the model of isolated liver with reperfusion was set upp,the expression of TNF-? mRNA was detected with RT-PCR in different preservation time of the isolated liver. Results In FK506-treated group, expression level of TNF-? mRNA was obviously lower(P