Paraoxonase 1 Gene Expression Is Associated with Chronic Renal Failure in the Hans of Hunan Province
- VernacularTitle:PON1基因表达与湖南汉族慢性肾衰发生有关
- Author:
Jun WEN
;
Hongbo WU
;
Lihua SONG
- Publication Type:Journal Article
- Keywords:
Paraoxonase-1;
Chronic renal failure;
Polymorphism
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship among paraoxonase-1 (PON 1) activity in serum,PON 1 Q192R polymorphism and chronic renal failure disease ( CRF ) in the hans of Hunan.Methods PON 1 activity in serum and PON 1 Q192R polymorphism of 79 patients with CRF and 90 healthy subjects as control were measured.Results PON 1 activity in serum of patients with CRF (372 6?150 6)U was significantly lower than that in control group (537 8?172 2)U(P