Expression of p27 and Cyclin D_1 Proteins and Their Significance in Non-Hodgkin's Lymphoma
- VernacularTitle:p27和cyclin D_1蛋白在非霍奇金淋巴瘤中的表达及其意义
- Author:
Yuenan LI
;
Jie JIANG
;
Hui ZHENG
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Cell cycle;
p27;
Cyclin
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study expression of p27 and cyclin D 1 proteins and their significance in non-Hodgkin's lymphoma (NHL).Methods The expression of p27 and cyclin D 1 proteins were detected by imunohistochemical technique in 77 cases of NHL.Results Of 77 NHLs, the positive rates of p27 and cyclin D 1 protein were 51 9% (40/77) and 58 4% (45/77) respectively, and the positive intensity of p27 in low grade group was significantly higher than in high grade group (P
