Incidence and Predictive Factors of Benign Renal Lesions in Korean Patients with Preoperative Imaging Diagnoses of Renal Cell Carcinoma.
10.3346/jkms.2011.26.3.360
- Author:
Seo Yong PARK
1
;
Seong Soo JEON
;
Seo Yeon LEE
;
Byong Chang JEONG
;
Seong Il SEO
;
Hyun Moo LEE
;
Han Yong CHOI
Author Information
1. Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. seongsoo.jeon@samsung.com
- Publication Type:Original Article
- Keywords:
Kidney Neoplasms;
Pathology;
Carcinoma, Renal Cell;
Incidence;
Benign
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Angiomyolipoma/diagnosis/epidemiology/surgery;
Carcinoma, Renal Cell/*diagnosis/epidemiology/surgery;
Child;
Cohort Studies;
Cysts/diagnosis/epidemiology/surgery;
Diagnostic Imaging;
Female;
Hematuria;
Humans;
Kidney Neoplasms/*diagnosis/epidemiology/surgery;
Male;
Middle Aged;
Nephrectomy;
Republic of Korea;
Retrospective Studies
- From:Journal of Korean Medical Science
2011;26(3):360-364
- CountryRepublic of Korea
- Language:English
-
Abstract:
The present study was performed to determine the incidence and predictive factors of benign renal lesions in Korean patients undergoing nephrectomy for presumed renal cell carcinoma on preoperative imaging. We analyzed the pathologic reports and medical records of 1,598 eligible patients with unilateral, nonmetastatic, and nonfamilial renal masses. Of the 1,598 renal masses, 114 (7.1%) were benign lesions, including angiomyolipoma in 47 (2.9%), oncocytoma in 23 (1.4%), and complicated cysts in 18 (1.1%) patients. On univariate analysis, the proportion of benign lesions was significantly higher in female patients, and in patients with smaller tumors, cystic renal masses, and without gross hematuria as a presenting symptom. When renal lesions were stratified by tumor size, the proportion of benign as opposed to malignant lesions decreased significantly as tumor size increased. On multivariate analysis, female gender, smaller tumor size, and cystic lesions were significantly associated with benign histological features. The findings in this large cohort of Korean patients show a lower incidence (7.1%) of benign renal lesions than those of previous Western reports. Female gender, cystic renal lesions, and smaller tumor size are independent predictors of benign histological features.
