A Study of Relationship Between Intelligence Condition of the Epileptic Patient and ?-GABA in CSF
- VernacularTitle:癫痫患者智能状况与脑脊液?-氨基丁酸的相关性研究
- Author:
Haifeng PENG
;
Shijun ZHOU
;
Hangjun TANG
- Publication Type:Journal Article
- Keywords:
Epilepsy;
Intelligence condition;
Cerebrospinal fluid;
?-aminobutyric acid
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the intelligence condition and the content of ?-aminobutyric acid (GABA) in cerebrospinal fluid (CSF) in epileptic patients.Methods We measured the Intelligence Quotient (IQ) of 40 cases of epileptic patients by using the Wechsler Intellectual Scaled, and tested their CSF-GABA contents by using HPLC.At the same time, factors which might have influence on patient’s IQ were analysed.Results In the 40 cases of epileptic patients, there were 14 cases of patients with FIQ≤89, and occupied 35%.The intelligence condition of epileptic patients was positive relation with the contents of CSF-GABA, education background and patterns of seizure,but was negative relation with the patient's age. Among all factors, content of CSF-GABA was very significant relationship with VIQ, PIQ and FIQ (P
