Relationship of Plasma TNF-? Levels and Insulin Resistance in the Patients with Type2 Diabetes
- VernacularTitle:2型糖尿病患者血浆TNF-?水平与胰岛素抵抗的关系
- Author:
Huiling CHEN
;
Zhidong XIE
;
Minxiang LEI
- Publication Type:Journal Article
- Keywords:
TNF-?;
Type 2 diabetes;
Insulin resistance
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To investigate the relationship between plasma tumor necrosis factor ?(TNF-?) and insulin resistance in the patients with non obese type 2 diabetes.Methods The levels of plasma TNF-? and serum insulin were measured in 38 patients with type 2 diabetes and 30 healthy subjects by immuno-radioassay. Insulin sensitive index (ISI) and body mass index(BMI) were also calculated. The correlation analysis was done between TNF-? and ISI.Results ⑴ The levels of plasma TNF-? in type 2 diabetes were 30 79?6 64fmol/ml, and higher than those in controls (P
