Relationship Between Expression of Survivin Gene and Biological Characteristics in Human Esophageal Carcinoma
- VernacularTitle:Survivin基因在食管癌中的表达与生物学特性的关系
- Author:
Weiguo ZHANG
;
Qingming WU
;
Xiaohu WANG
- Publication Type:Journal Article
- Keywords:
Survivin;
Esophageal carcinoma
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between expression of Survivin gene and biological characteristics in human esophageal carcinoma.Methods The expression of Survivin gene was detected in 62 cases of esophageal carcinoma tissues and tumor-adjacent normal tissues by immunohistochemical technique.Results The positive rate of Survivin expression in esophageal carcinomas was 79 0%,which was higher than that in tumor-adjacent normal tissues(6 5%,P0 05). The positive rate of Survivin expression in lymph node metastasis group (93 1%) was higher than that in the group without lymph node metastasis (66 7%,P