Expression of ?-catenin in Human Carcinomas of Alimentary System and its Significance
- VernacularTitle:?-连环素在消化系统肿瘤中的表达及其意义
- Author:
Liang HAN
;
Shiqiang SHEN
;
Shilun TONG
- Publication Type:Journal Article
- Keywords:
catenin;
Gastric carcinomas;
Colorectal carcinomas;
Human hepatic carcinomas;
Immumohistochemistry
- From:
Journal of Chinese Physician
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the significance of ?-catenin expression in human gastric carcinomas, colorectal carcinomas and human hepatic carcinomas.Methods S-P immunohistochemical method was used to detect ?-catenin expression in 80 cases of human carcinomas of alimentary system and corresponding tumor-adjacent normal tissues by ?-catenin polyclonal antibody. The results were analyzed using densitometrically semiquantitated .Results ?-catenin were normally expressed in all tumor-adjacent normal tissues of digestive system. ?-catenin expression was reduced or negative in human carcinomas of alimentary system (P
