Detection of IL-4、IFN-?、and TGF-?1 in Patients with Dermatomyositis/Polymyositis
- VernacularTitle:皮肌炎/多发性肌炎患者白介素4、干扰素?、转化生长因子?1的检测
- Author:
Aiming CHEN
;
Qing LIU
;
Boyuan QIAN
;
Qunxin PENG
;
Yun WU
- Publication Type:Journal Article
- Keywords:
Dermatomyositis;
Polymyositis;
Interleukin-4;
Interferon typeⅡ;
Transforming growth factor beta
- From:
Chinese Journal of Dermatology
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the polarization of Th1/Th2/Th3cell function of dermatomyositis/polymyositis(DM/PM).Methods The culture supernatant levels of IL-4,IFN-?,TGF-?1that were produced by the peripheral blood mononuclear cells(PBMC)were detected by Sandwich ELISA in23DM/PM patients(DM18,PM5)and17healthy subjects.Results The level of IFN-?(168.17?218.35ng/mL)produced by PBMC from the patients of DM/PM was significantly lower than that from normal controls(380.61?299.13ng/mL)(P0.05),and normal controls(231.64?83.92)(P
